In the longitudinal study of 150 chronic ketamine users discussed above, increased depression score (Beck Depression Inventory), but not clinical depression, was associated with frequent (daily) current and previous ketamine use. Depression scores were not increased in less frequent (less than three times per week) ketamine users. There have been some pilot studies that have investigated the use of ketamine as an antidepressant in patients with depression and of intravenous ketamine in patients with resistant depression. The results of these preliminary studies are not conclusive, but suggest that ketamine may have a role in this setting.
Neurological and Cognitive Effects
A number of studies have shown that acute Ketamine online use results in impairment of both working and episodic memory; it appears that these effects are greater in men than in women. Long-term ketamine use is also associated with deficits of both long- and short-term memory. Many of these studies … Read More